A Stereological Method for the Quantitative Evaluation of Cartilage Repair Tissue

A Stereological Method for the Quantitative Evaluation of Cartilage Repair Tissue

OBJECTIVE To implement stereological principles to develop an easy applicable algorithm for unbiased and quantitative evaluation of cartilage repair. DESIGN Design-unbiased sampling was performed by systematically sectioning the defect perpendicular to the joint surface in parallel planes providing 7 to 10 hematoxylin-eosin stained histological sections. Counting windows were systematically s...

The Tissue Engineered Approaches for Cartilage Repair

Technological improvements in biology, medicine, chemistry, engineering and material science have allowed deeper insights into the architectural and molecular organization levels of tissues and materials, providing innovative approaches and tools for medical treatments. One of the therapeutic targets that may benefit from these new issues is damaged human articular cartilage, a tissue unable to...

Non-Invasive Evaluation Method for Cartilage Tissue Regeneration Using Quantitative-MRI

Quantitative evaluation of mechanical properties in tissue-engineered auricular cartilage.

Tissue-engineering (TE) efforts for ear reconstruction often fail due to mechanical incompetency. It is therefore key for successful auricular cartilage (AUC) TE to ensure functional competency, that is, to mimic the mechanical properties of the native ear tissue. A review of past attempts to engineer AUC shows unsatisfactory functional outcomes with various cell-seeded biodegradable polymeric ...

investigating the feasibility of a proposed model for geometric design of deployable arch structures

deployable scissor type structures are composed of the so-called scissor-like elements (sles), which are connected to each other at an intermediate point through a pivotal connection and allow them to be folded into a compact bundle for storage or transport. several sles are connected to each other in order to form units with regular polygonal plan views. the sides and radii of the polygons are...